Infantile spasms or epileptic spasms remain one of the most catastrophic seizure types in childhood. West syndrome is an age-dependent expression of a damaged brain and most patients with infantile spasms have some degree of developmental delay. Although the unifying epileptogenic mechanism is unknown, various underlying disorders cause ISs. These disorders are often classified into prenatal, perinatal and postnatal groups. Symptoms associated with West syndrome usually begins during the first year of life. The average age of onset for epileptic spasms is at 6 months. About 70-80% of patients have abnormal findings on neuroimaging studies. In general, corticosteroids and vigabatrin remain the most commonly used treatments, but other therapies are also widely prescribed.
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